Full Idea
Quine has argued tirelessly that syntax and 'semantics' are indeterminate, and linguistic semantics of the sort that is currently in favor is a pseudoscience and a pipe dream.
Gist of Idea
Syntax and semantics are indeterminate, and modern 'semantics' is a bogus subject
Source
report of Willard Quine (Methodological Reflections on Current Linguistic Theory [1972]) by William Lycan - The Trouble with Possible Worlds 02
Book Reference
'The Possible and the Actual', ed/tr. Loux,Michael J. [Cornell 1979], p.281
A Reaction
I think the defence of such things is that they may not integrate into science very well (or even integrate at all), but semantics is intended to integrate into philosophy, and is motivated by philosophical concerns. Quine may be right!