Full Idea
Since all effect consists in that which happens, consequently in the changeable, which indicates succession in time, the ultimate subject of the changeable is therefore that which persists, as the substratum of everything that changes, i.e. the substance.
Gist of Idea
Substance must exist, as the persisting substratum of the process of change
Source
Immanuel Kant (Critique of Pure Reason [1781], B250/A205)
Book Reference
Kant,Immanuel: 'Critique of Pure Reason', ed/tr. Guyer,P /Wood,A W [CUO 1998], p.313
A Reaction
The idea that 'something' changes seems to involve a commitment to substances, but not if one thing is replaced by another. It is not clear that the abandonment of the concept of substance leads to a total collapse of our metaphysics.