Full Idea
What is the greatest thing you can experience? It is the hour of the great contempt. The hour in which even your happiness grows loathsome to you, and your reason and your virtue also.
Gist of Idea
The greatest experience possible is contempt for your own happiness, reason and virtue
Source
Friedrich Nietzsche (Thus Spake Zarathustra [1884], 1.01)
Book Reference
Nietzsche,Friedrich: 'Thus Spake Zarathustra', ed/tr. Hollingdale,R.J. [Penguin 1969], p.42
A Reaction
This would be a transient state for Nietzsche, in which you realise the hollowness of those traditional ideas, and begin to seek something else.