Full Idea
Opposition to reason deserves the name of madness.
Gist of Idea
Opposition to reason is mad
Source
John Locke (Essay Conc Human Understanding (2nd Ed) [1694], 2.33.04)
Book Reference
Locke,John: 'Essay Concerning Human Understanding', ed/tr. Nidditch,P.H. [OUP 1979], p.395
A Reaction
This may just be a tautology, based on the meaning of the word 'madness', but it sounds more like a clarion call for the Englightenment.