Full Idea
NO physical mechanism seems very intuitively plausible as a seat of qualia, least of all a brain.
Gist of Idea
A brain looks no more likely than anything else to cause qualia
Source
Ned Block (Troubles with Functionalism [1978], p. 78)
Book Reference
'The Philosophy of Mind', ed/tr. Beakley,B /Ludlow P [MIT 1992], p.78
A Reaction
I'm not sure about "least of all", given the mind-boggling complexity of the brain's connections. Certainly, though, nothing in either folk physics or academic physics suggests that any physical object is likely to be aware of anything.